About Angioplasty:

• It is a minimally invasive procedure used to widen a narrowed or blocked blood vessel, often using a balloon catheter and, when indicated, a stent.
• It most commonly treats atherosclerosis (a collection of plaque made of fat and cholesterol) in arteries.
• Angioplasties are often necessary to try to prevent serious complications of atherosclerosis, like heart attack and stroke.
• Types of angioplasty: The two most common include:
  • Coronary artery angioplasty
  • Peripheral artery angioplasty
• Different angioplasty techniques include:
  • Balloon angioplasty
  • Angioplasty with or without stenting
  • Excimer Laser Coronary Angioplasty (ELCA)

About Emerging Science, Technology, and Innovation Conclave (ESTIC):

• It is India's premier STI platform, bringing together ministries, innovators, and global visionaries.
• A flagship annual event, ESTIC fosters collaboration, showcases disruptive innovation, and drives forward the vision of "Viksit Bharat 2047."
• It will showcase cutting-edge research, deep-tech breakthroughs, and thought-provoking discussions with Nobel Laureates, global experts, policymakers, and emerging leaders - igniting a new era of scientific leadership.
• ESTIC 2026:
  • Theme: “Creative Minds, Catalysing Science, Empowering Technologies.” 
  • It is organised by the Council of Scientific and Industrial Research (CSIR) under the guidance of the Office of the Principal Scientific Adviser to the Government of India.

About Macrophages:

• Macrophages are specialised white blood cells (WBCs) that play an important role in the body's immune system by engulfing and destroying pathogens, dead cells, and cellular debris.
• Most macrophages develop from monocytes, a type of WBC produced in the bone marrow. Some tissue-resident macrophages originate from embryonic cells.
• Macrophages do not travel through the blood. Instead, they remain in one part of the body, within specific tissues.
• Types:
  • Macrophages have two modes (phenotypes):
    • M1, or inflammatory mode: M1 macrophages destroy germs and cancer cells and alert immune cells to infections.
    • M2, or anti-inflammatory mode: M2 macrophages help with wound healing, clearing out dead cells, and tissue repair.
• Macrophages are known for their ability to destroy foreign substances that get into the body. They also help in:
  • Activating B cells and T cells, which helps them target pathogens.
  • Removing dead and damaged cells.
  • Releasing proteins like cytokines that alert other immune cells to infections.
  • Repairing tissue, healing wounds, and reducing inflammation.
  • Breaking down old red blood cells and recycling the iron.
  • Regulating fetal tissue development.
  • Regulating organ function and maintaining homeostasis.
• How do they work?
  • Macrophages have receptors on the outside that they use like antennae. These antennae get signals from substances in the environment around them.
  • If a macrophage detects something it should get rid of, it swallows or “eats” it (a process called phagocytosis, or “cell eating”).

About Kittur Fort:

• It is located in Karnataka.
• History:
  • It was constructed by Allappa Gowda Sardesai, the fifth ruler of the Kittur dynasty during his rule between 1660 and 1691 AD.
  • It became famous as the stronghold of Rani Chennamma, a brave queen who led one of India’s earliest armed rebellions against British rule in 1824, about 33 years before the 1857 revolt.
  • Though the British eventually suppressed the uprising, it remains a significant event in India's struggle for freedom.
• Architecture:
  • The fort was constructed using black basalt and features Peshwa-Islamic architecture, with a three-storeyed palace inside.
  • The fort was equipped with secret water wells, a pole star viewing room, and a large palace hall for royal gatherings.
  • A museum within the fort houses weapons, sculptures, and relics from the era of Queen Kittur Chennamma’s rebellion.
  • The fort features well-preserved ruins, including the old palace, a watchtower, water cisterns, and ancient temples.

About Neoterpnosia mawphlangensis:

• It is a new species of cicada.
• It was discovered in forests of Mawphlang in Meghalaya’s East Khasi Hills.
• It is distinguished by characteristic structures in the male reproductive organs, along with distinctive markings on its transparent wings.
• It is active mainly around dawn and calls from the upper branches and foliage of subtropical pine forests.

What are Cicadas?

• Cicadas are insects belonging to the superfamily Cicadoidea, within the order Hemiptera. They are known for their loud, species-specific calls, produced by males using specialised organs called tymbals.
• They are known for their loud, complex and species-specific acoustic signals or songs.
• They are found worldwide, with the highest diversity occurring in tropical regions.
• The lifespan of cicadas varies depending on the species and whether they are annual or periodical cicadas.
• Male cicadas produce loud calls using specialised organs called tymbals, located on their abdomen, to attract females.

About National Startup Awards:       

• It is a flagship initiative launched in 2019 under the Startup India initiative to recognise innovation and entrepreneurship and strengthen India’s startup ecosystem.
• It provides a national platform to recognise entrepreneurial excellence and showcase innovative solutions addressing critical challenges across sectors.
• It recognises startups demonstrating outstanding performance in innovation, scalability, sustainability and socio-economic impact.
• Nodal Ministry: Ministry of Commerce and Industry

National Startup Awards 6.0:

• NSA 6.0 edition aims to encourage participation from startups across States and Union Territories, including emerging entrepreneurial ecosystems in Tier-2 and Tier-3 cities.
• It will recognise innovation, entrepreneurship and excellence across 20 sectoral categories and three special award categories,
• This edition introduces 12 new sectoral categories:
  • Biomanufacturing; Consumer Industries; Defence & Security; Rural Economy, Traditional Industries & Livelihoods; Education & Skilling; Electronics, Semiconductors & Advanced Manufacturing; Sports, Fitness & Sports-Tech; Future Mobility & Automotive; Ocean & Blue Economy; Space-Tech, Drones & Aerospace; Telecom, Connectivity & Digital Infrastructure; and Travel, Tourism & Hospitality.
• The three special award categories are:
  • Women-Led Startups
  • Startups from the North-Eastern Region
  • Student Innovator / Aspiring Entrepreneur
• Award Money:
  • Winning startups across the 20 sectoral categories and the two startup-focused special categories will be eligible for a cash prize of ₹25 lakh per category.
  • The Student Innovator / Aspiring Entrepreneur Award will carry a total prize pool of ₹25 lakh across four sub-categories.
  • In addition this award seeks to facilitate mentorship, investor engagement, market access, industry partnerships and enhanced visibility within India’s startup ecosystem.

About Allocaecilius Nilgiriensis:

• It is a new barklice species, discovered in Nilgiri Hills.
• It is only the second time a member of this unique barklouse genus has ever been recorded in the country. It brings the total number of known Allocaecilius species worldwide to thirteen.
• Distribution: It is found across the lush landscapes of the Southern Western Ghats in Tamil Nadu and Keralam.
• Habitat: These tiny barklice are specialised inhabitants restricted to the damp, shaded canopies and understories of high-altitude shola and evergreen rainforests in the southern Western Ghats.
• Barklice are a vital microscopic clean-up crew, grazing harmlessly on the surface of tree bark, feeding on mould, fungi, algae, lichens, and dead organic debris
• Appearance:
  • It has distinctive brown patches located in specific distal of its forewings, alongside specialised thumb-like structures on the male's lower abdomen (hypandrium) and a deeply indented subgenital plate in females.

About Exercise Garuda Shakti:           

• It is the joint Special Forces exercise conducted between India– Indonesia.
• Participating Troop: The Indian contingent comprises troops from the Parachute Regiment (Special Forces).
• Aim: The exercise aims to strengthen mutual understanding, cooperation and interoperability between the Special Forces of the two nations.
• Focus: It focuses on tactics, techniques and procedures for special operations in jungle environments, including obstacle crossing, combat marksmanship, mountaineering, air assault training and combat-hardening sessions.
  • It also includes the exchange of expertise and information on weapons, equipment and operational practices.
• Objective: The joint training will culminate with a validation exercise designed to simulate realistic operational scenarios and assess the endurance, coordination and combat readiness of both contingents.
• Significance: It will further strengthen defence cooperation and bilateral relations between India and Indonesia.

About International Convention against Doping:    

• It is a UNESCO multilateral treaty by which States agree to adopt national and international measures to prevent and eliminate doping in sport.
• Background: The Convention was adopted during the 33rd session of UNESCO’s General Conference (19 October 2005) and entered into force on 1 February 2007.
• It is the only legally binding international instrument committed to promoting integrity and eliminating doping in sport globally.
• Members: It consists of 192 States Parties, making it UNESCO’s second most ratified treaty.
  • India is a signatory to the International Convention Against Doping in Sport.
• Aim: The Convention aims to harmonize anti-doping legislation, guidelines, regulations, and rules internationally in order to provide a level and safe playing environment for all athletes.
• Governance: The Conference of Parties (COP) is the sovereign body of the Convention, meeting in ordinary session biennially.
• It has overall responsibility for its implementation and evolution.
• Features of International Convention against Doping in Sport:
  • The convention allows governments to formally recognize the World Anti-Doping Agency (WADA) and the Code. 
  • It works under a positive implementation approach, providing guidance, financial support, skill-training and capacity-building to empower States Parties aiming to enhance their implementation of the Convention.
  • It also provides a global forum for public and private stakeholders of the sport integrity ecosystem.
  • Funding mechanism: Anti-Doping Fund was formed to create awareness about doping.

About Orange Oakleaf Butterfly:      

• It is a nymphalid butterfly found in Tropical Asia from India to Japan.
• Appearance: It is known for its remarkable camouflage. With its wings folded, it closely resembles a dry, withered leaf. When it spreads its wings, it reveals bright orange, jet-black and deep velvety blue colours.
• Habitat:
  • It is commonly found in subtropical and temperate forest zones, especially in areas with dense undergrowth and ample leaf litter.
  • It thrives in altitudes ranging from 500 to 2000 meters and is often spotted near riverbanks, shaded forest trails, and damp patches where it feeds on fermenting fruit and tree sap.
• Behavior: It is also known to mud-puddle.
• Unlike many butterflies, the Orange Oakleaf is not drawn to flowers. Instead, it is attracted to rotting fruit and tree sap.
• Ecological Significance: It acts as a pollinator and its presence also signifies healthy forest habitats, as it relies on dense vegetation and leaf litter for survival.