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16 Jan 2026

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Questions : 50 Questions

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Expiry Date : May 31, 2026, 11:59 p.m.

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Test Series : Prelims CAMP 2026 - Online Batch 4
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Daily MCQ
27 minutes ago

16 January 2026 MCQs Test

10 Questions 20 Minutes

Article
16 Jan 2026

Gujarat’s BSL-4 Facility: India’s State-Backed Lab for Deadliest Pathogens

Why in news?

Union Home Minister Amit Shah laid the foundation stone for India’s first state-funded Bio-Safety Level 4 (BSL-4) containment facility in Gandhinagar.

Describing it as a “health shield” for the nation, he said the laboratory marks the start of a new era in India’s health security and biotechnology capabilities.

What’s in Today’s Article?

  • About BSL-4 Facility
  • Gujarat’s State-Funded BSL-4 Laboratory
  • Existing BSL-4 and ABSL-4 Facilities in India
  • India’s Expanding Biosafety Laboratory Network

About BSL-4 Facility

  • A Bio-Safety Level 4 (BSL-4) facility represents the highest level of biological containment, designed to safely handle the world’s most dangerous and highly infectious pathogens, many of which lack effective vaccines or treatments.
  • Operating under stringent international safety standards, these laboratories enable advanced research on deadly diseases, including the development of diagnostics, vaccines, and therapeutics, as well as rapid outbreak investigation and response.
  • India’s upcoming BSL-4 laboratory in Sector-28 of Gandhinagar, along with an Animal Bio-Safety Level (ABSL) facility, will serve as a strategic national asset for research on some of the deadliest known pathogens.
  • This will strengthen the country’s health security and bio-preparedness.

Gujarat’s State-Funded BSL-4 Laboratory

  • The BSL-4 laboratory being built in Gandhinagar, Gujarat, will be India’s first fully state-funded and state-controlled BSL-4 facility and the second civilian BSL-4 research lab in the country.
  • Spread over 11,000 sq metres and costing ₹362 crore, it is being developed under the Gujarat State Biotechnology Mission.
  • Institutional Framework and Timeline
    • The facility will operate under the Gujarat Biotechnology Research Centre, which already houses a BSL-2+ laboratory and played a key role during the Covid-19 pandemic by sequencing the SARS-CoV-2 genome.
    • Planning for the BSL-4 lab began in mid-2022, with the foundation stone laid on January 13, 2026.
  • Infrastructure and Safety Standards
    • The complex will include BSL-4, BSL-3, BSL-2, ABSL-4, and ABSL-3 laboratory modules, along with advanced utilities and support systems.
    • It is being developed in line with international biosafety guidelines issued by the Centers for Disease Control and Prevention, National Institutes of Health, Department of Biotechnology, and Indian Council of Medical Research.
  • Role in Disease Control and Vaccine Research
    • The lab will strengthen Gujarat’s and India’s capacity to respond in real time to outbreaks of deadly human diseases and zoonotic infections.
    • It will also support advanced research into diagnostics, vaccines, and therapeutics.
    • The ABSL-4 component will allow animal disease research and vaccine production using antibodies derived from animals—work that earlier required sending samples to ICAR–National Institute of High Security Animal Diseases.
  • National Facility and Expert Oversight
    • The Department of Biotechnology has signed an MoU designating the lab as a national facility, ensuring guidance from expert institutions across India.
    • Officials note that the lab will remove long-standing bottlenecks caused by the lack of BSL-4 infrastructure in the country.

Existing BSL-4 and ABSL-4 Facilities in India

  • Civilian BSL-4 Laboratories - India currently has only one functional civilian BSL-4 laboratory, located at the National Institute of Virology in Pune, Maharashtra. This facility handles research on the most dangerous human pathogens.
  • Defence-Sector BSL-4 Facility - In late 2024, the Defence Research and Development Organisation established its own BSL-4 laboratory in Gwalior, Madhya Pradesh, under the Defence Ministry, expanding India’s high-containment research capacity.
  • High-Security Animal Disease Laboratories
    • India has two major laboratories studying high-risk zoonotic diseases:
      • The National Institute of High Security Animal Diseases (ICAR–NIHSAD) in Bhopal, currently rated ABSL-3+, with plans announced in June 2025 to upgrade it to ABSL-4.
      • The International Centre for Foot and Mouth Disease (ICAR–ICFMD) in Bhubaneswar, Odisha, which operates with an ABSL-3Ag rating.
  • Global Context
    • Officials note that globally about 69 BSL-4 laboratories are operational or under development, underscoring India’s relatively limited but gradually expanding presence in high-containment biological research infrastructure.

India’s Expanding Biosafety Laboratory Network

  • As of March 2025, the Ministry of Health and Family Welfare, through the Department of Health Research, has approved 165 biosafety laboratories under the Virus Research and Diagnostic Laboratories (VRDL) scheme.
  • This includes 154 BSL-2 and 11 BSL-3 labs aimed at epidemic preparedness and disaster response.
  • ICMR-Led Biosafety Facilities - Beyond VRDLs, the Indian Council of Medical Research has established 21 biosafety laboratories across its institutes, comprising 1 BSL-4, 8 BSL-3, and 12 BSL-2 facilities.
  • Science & Technology–Supported Labs - Under the Department of Science and Technology, the Anusandhan National Research Foundation has funded 5 BSL/ABSL-3 laboratories through the Intensification of Research in High Priority Areas (IRHPA) programme.
  • Biotechnology, Agriculture, and Industrial Research
    • The Department of Biotechnology has set up 26 biosafety laboratories across DBT institutes.
    • The Indian Council of Agricultural Research has established 9 biosafety laboratories.
    • The Council of Scientific and Industrial Research has created 11 biosafety laboratories across its network.
  • Overall Picture
    • Together, these initiatives reflect a broad-based expansion of India’s biosafety infrastructure—anchored by BSL-2 and BSL-3 capacity—with targeted investments in high-containment labs to strengthen national preparedness for infectious disease threats.
Science & Tech

Article
16 Jan 2026

Grok controversy: X Curtails Grok After Backlash

Why in news?

X, owned by Elon Musk, has restricted its Grok AI tool from generating sexualised images of women and children following widespread global criticism.

The decision represents a clear retreat after Musk initially placed responsibility on users creating such content and later claimed ignorance about the tool’s misuse involving children.

Escalating regulatory scrutiny across multiple countries ultimately compelled the platform to curb the AI’s image-generation capabilities.

What’s in Today’s Article?

  • Grok Controversy: AI-Generated Sexualised Images and Safety Gaps
  • Initial Response to the Backlash
  • Regulatory Pressure Triggers the Rollback

Grok Controversy: AI-Generated Sexualised Images and Safety Gaps

  • A December 2025 update to Grok enabled users to generate sexualised and objectionable images of women and children using existing photographs, often without consent or knowledge.
  • Users prompted the AI to digitally undress women or place them in suggestive poses, with the generated images appearing publicly in comment threads, leading to harassment.
  • Instances involving children further intensified concerns, highlighting serious gaps in AI safeguards and content moderation on X.

Initial Response to the Backlash

  • Following global outrage over Grok-generated sexualised images, Elon Musk stated that users generating illegal content with Grok would face the same consequences as those uploading illegal material directly to X.
  • Musk emphasised that Grok generates images only in response to user prompts and does not act autonomously.
  • He asserted that the AI is designed to refuse illegal requests and comply with the laws of the relevant country or state.
  • Denial of Knowledge and Technical Explanation
    • Recently, Musk denied any awareness of Grok being used to create sexualised images of children, claiming there were “literally zero” such instances to his knowledge.
    • He suggested that any unexpected behaviour could result from adversarial hacking, which the company fixes promptly.
  • Platform-Level Restrictions
    • Before the final rollback, X had restricted Grok’s image-generation features to paid users.
    • However, within hours of Musk’s denial, the company announced a complete shutdown of Grok’s ability to generate sexualised images, regardless of user status.
    • The move marked a clear reversal by X, effectively acknowledging the severity of the issue and responding to mounting regulatory and public pressure by removing the problematic functionality altogether.

Regulatory Pressure Triggers the Rollback

  • X’s decision to restrict Grok followed strong regulatory action, beginning with a stern notice from the Government of India.
  • After being flagged for failing to meet due diligence obligations under the Information Technology Act, 2000 and related rules, X removed about 3,500 pieces of content and blocked 600 accounts, admitting lapses in compliance.
  • The controversy quickly spread beyond India. In the United Kingdom, an impending legal change is set to criminalise the creation of such sexualised images.
  • Malaysia and Indonesia blocked access to Grok and initiated legal action against X and xAI, citing failures to prevent harmful content and protect users.
  • In the US, the California Attorney General announced an investigation into Grok and xAI over the generation of objectionable images, adding to mounting legal pressure on the platform.
  • X’s New Restrictions and Safeguards
    • In response, X announced technological measures to prevent Grok from editing images of real people into revealing clothing, including bikinis, applying the restriction to all users.
    • The platform also limited image creation and editing via Grok to paid subscribers and introduced geoblocking in jurisdictions where such content is illegal.
    • X reiterated its commitment to platform safety, stating it has zero tolerance for child sexual exploitation, non-consensual nudity, and unwanted sexual content, marking a decisive retreat under sustained global regulatory scrutiny.
Social Issues

Article
16 Jan 2026

The New Grammar of Indian Elections - Media, Misinformation and Manipulation

Context:

  • With elections due in four States and one Union Territory in about 10 weeks, India’s electoral landscape is once again witnessing the fusion of politics, media, and technology.
  • From WhatsApp-driven mobilisation (2019) to digital-forward campaigns (2024), Indian elections are evolving rapidly.
  • While 2029 is predicted to be the “AI election”, the 2026 elections reflect a hybrid ecosystem—a mix of traditional media, social media, influencers, and artificial intelligence.
  • This raises serious concerns about fake news, influencer politics, and deepfakes, with implications for electoral integrity and democratic accountability.

Changing Media–Politics Interface in India:

  • Campaigns now extend beyond rallies to reels, podcasts, jingles, AI-generated calls, and algorithm-driven content.
  • Votes are cast offline, but perceptions are shaped online, making digital platforms the primary battleground.

Fake News - A Structural Feature of Elections:

  • What is fake news?
    • While there is no legal definition of fake news in India, Australia’s eSafety Commissioner defines it as “fictional news stories made up to support certain agendas”.
    • It is often described as “yellow journalism on steroids”, amplified by algorithms.
  • Why it matters in elections?
    • Fake news directly impacts voter perception, polarisation, and trust in institutions.
    • With over 90 crore internet users in India in 2025, influencing perception and shaping narratives has become possible with just a few clicks.
    • For example, a study by the Indian School of Business and CyberPeace revealed that 46% of all fake news was political in nature.
  • Who is affected: 3 out of 5 Indians access news online. A Pew Research Centre study of 2025 found that 65% of those surveyed viewed made-up news and information as a huge concern, among the highest globally.
  • When does it peak: During elections - NCRB recorded a 70% rise in fake news cases in 2019, an election year.
  • Where does it spread?
    • Social media and messaging platforms - WhatsApp, X, Facebook, Instagram.
    • AI-generated visuals, doctored videos, synthetic clips blur fact and fiction. Algorithms provide virality without accountability.

Media Consumption Patterns - Digital Dominance:

  • India has close to 900 private television channels, and nearly half of them are news channels. Television still has a deep reach — 23 crore homes own a TV set.
  • However, shift to digital is decisive -
    • 7 in 10 Indians prefer online news (Reuters Institute).
    • News sources - YouTube (55%), WhatsApp (46%), Instagram (37%), and Facebook (36%).
  • Even with these media consumption patterns, newspapers, both in regional languages and English, still remain comparatively high on the credibility quotient.

Influencers - The New Political Intermediaries:

  • Influencers wield significant agenda-setting power, backed by professional research and production teams.
  • Gen Z trends: Only 13% follow celebrities, 86% prefer influencers.
  • Political outreach:
    • Senior politicians and parties actively engage influencers. Union Government empanelled influencer agencies via MyGov (2023).
    • There are concerns over political bias, as at least one empanelled agency’s leadership openly supports the ruling dispensation.

Deepfakes - AI as a Political Weapon:

  • Nature of the threat: Digitally altered or AI-generated videos and audio impersonating leaders and celebrities. For example,
    • Deceased political leaders “addressing” meetings.
    • Film actors criticising or endorsing political parties.
  • Scale of the problem:
    • In the 60 days before the last Lok Sabha elections 5 crore AI-generated calls were made to voters using synthetic voices.
    • Meta approved 14 AI-generated ads inciting violence against Muslims and an opposition leader.
  • Institutional failure:
    • The Election Commission of India (ECI), as a constitutional authority under Article 324, should regulate electoral communication.
    • However, weak implementation capacity (e.g., recent SIR process) raises doubts about its preparedness to handle AI-driven misinformation.

Challenges and Way Ahead:

  • Absence of a legal definition of fake news: Legal clarity - define fake news and deepfakes within electoral and IT laws.
  • Algorithmic amplification without transparency: Platform accountability - Algorithmic transparency, faster takedown mechanisms during election periods.
  • Lack of robust regulation of political influencers: ECI-led regulatory framework mandatory disclosure of AI-generated political content, clear guidelines for influencers and political advertising.
  • Rapid proliferation of deepfakes and synthetic media: Strengthen inter-agency coordination (ECI, MeitY, platforms, civil society).
  • Institutional inertia and regulatory gaps: Within ECI and digital governance frameworks. Independent oversight bodies for election-time digital content moderation.
  • Threats: To free and fair elections, voter autonomy, and democratic trust. Digital literacy and media awareness campaigns for voters.

Conclusion:

  • Indian elections are entering a phase where technology is no longer just an enabler but a disruptor of democracy.
  • Fake news, influencers, and deepfakes have become structural features of electoral politics, challenging the foundations of free, fair, and informed choice.
  • As India moves towards an AI-driven electoral future, institutional preparedness, regulatory foresight, and citizen awareness will determine whether technology strengthens democracy or subverts it.
  • For the world’s largest democracy, the credibility of elections is inseparable from the credibility of information.
Editorial Analysis

Article
16 Jan 2026

India’s Road Safety Crisis - Engineering Gaps and Rising Fatalities

Why in the News?

  • A recent national report has identified India’s deadliest districts for road accidents, revealing that most fatalities are linked to infrastructure and systemic failures rather than traffic violations.

What’s in Today’s Article?

  • Road Safety Scenario (Statistics, Key Factors Behind Fatalities, etc.)
  • News Summary

India’s Road Safety Scenario

  • India records the highest number of road accident deaths globally, far exceeding other major countries.
  • Despite having the world’s second-largest road network, road safety outcomes remain poor.
  • According to recent estimates, nearly 3.5 lakh people died in road accidents during 2023-24, highlighting the scale of the crisis.
  • Road safety in India has traditionally focused on driver behaviour, such as speeding or drunk driving.
  • However, emerging evidence shows that this approach alone is insufficient, as deeper structural issues dominate accident causation.

Key Structural Factors Behind Road Fatalities

  • The report underlines that 59% of road accident fatalities occurred without any traffic violation, clearly pointing to road engineering deficiencies as a primary cause of deaths. These include:
    • Poor road design and alignment
    • Absence or damage of crash barriers
    • Inadequate signage and road markings
    • Insufficient street lighting
    • Unsafe junctions and pedestrian crossings
  • Such defects convert routine travel into a high-risk activity, especially on rural roads and highways.

Geographic Concentration of Road Accidents

  • Road fatalities in India are highly concentrated rather than evenly spread.
  • The report identifies 100 districts accounting for more than 25% of total road deaths over two years. Among them:
    • Nashik Rural and Pune Rural recorded the highest number of severe accidents.
    • Other high-fatality districts include Patna, Ahmednagar, Purba Midnapur, and Belagavi.
    • States such as Uttar Pradesh, Tamil Nadu, Maharashtra, Karnataka, and Rajasthan dominate the list.
  • This concentration indicates that targeted interventions in specific districts can yield substantial reductions in fatalities.

Nature and Timing of Fatal Accidents

  • The report highlights clear accident patterns:
    • 53% of deaths occurred between 6 PM and midnight, reflecting poor visibility and fatigue-related risks.
    • Rear-end, head-on, and pedestrian crashes accounted for 72% of fatalities.
    • Speeding contributed to only 19% of deaths, while rash driving and dangerous overtaking together accounted for less than 10%.
  • This challenges the perception that driver misconduct alone is responsible and shifts attention to road design and traffic management failures.

Emergency Response and Medical Gaps

  • Post-accident response remains weak:
    • Only about one-fifth of victims used the government 108 ambulance services.
    • A majority were transported using private vehicles or private ambulances, delaying critical care.
    • Hospital readiness and trauma care infrastructure vary widely across districts.
  • Delayed medical response significantly increases mortality, making emergency preparedness a crucial pillar of road safety.

News Summary: Findings and Recommendations of the Report

  • The joint report by the Ministry of Road Transport and Highways and SaveLIFE Foundation provides a clear roadmap for action:
    • Focus on known crash-prone locations rather than spreading resources thinly.
    • Conduct Road Safety Surveys on critical corridors by NHAI and state PWDs.
    • Implement site-specific engineering corrections based on Indian Road Congress and MoRTH guidelines.
    • Strengthen policing capacity at high-fatality police station jurisdictions.
    • Improve emergency response by expanding effective coverage of 108 ambulance services.
    • Use existing schemes more efficiently instead of launching new ones.
  • The report stresses that reducing road deaths requires better coordination, clearer accountability, and sustained leadership, not additional laws or schemes.

 

Economics

Article
16 Jan 2026

Early Investment in Children, the Key to India’s Future

Context

  • India’s aspiration to become a developed (‘Viksit’) nation and a $30 trillion economy by 2047 has become a defining narrative in contemporary public discourse.
  • While this vision is both desirable and attainable, it cannot be realised solely through investments in infrastructure, manufacturing, and digital innovation.
  • Developmental transitions historically succeed when nations prioritise human capital formation as much as physical capital.
  • In India, however, one critical dimension of human development remains under-recognised: Early Childhood Care and Development (ECCD).
  • Far from being a welfare concern, ECCD represents a strategic economic investment with long-term implications for productivity, equity and national competitiveness.

The Importance of the Early Years

  • Scientific evidence highlights the first 1,000 days of life, from conception to age two, as the period during which up to 85% of brain development and most neural connections are formed.
  • Extending this window to eight years totals roughly 3,000 days, during which foundational cognitive, emotional, social and behavioural capacities take shape.
  • Children who receive adequate nutrition, responsive care and cognitive stimulation during this period are more likely to complete schooling, acquire skills and contribute productively as adults.
  • At a macro level, such cohorts reduce future public expenditure on healthcare and remedial education and expand the taxable workforce, demonstrating that ECCD generates durable, intergenerational returns.

India’s Progress and Remaining Gaps

  • India’s own experience in child health illustrates the power of sustained investment.
  • Over the past decades, programmes such as the Integrated Child Development Services (ICDS), the Child Survival and Safe Motherhood initiative and the National Health Mission significantly reduced infant and child mortality and improved immunisation and nutrition outcomes.
  • However, these efforts largely targeted survival, not developmental potential. Moreover, ECCD interventions have predominantly focused on low-income households.
  • This targeted approach overlooks developmental challenges increasingly observed in middle- and upper-income families, including obesity, digital overexposure, reduced physical activity and delayed socio-emotional skills.
  • Developmental risk is therefore more universal than assumed.

The Case for Early and Integrated Interventions

  • Advances in neuroscience and epigenetics reinforce the need for interventions earlier than current policy frameworks provide.
  • Parental nutrition, mental health, substance use and environmental exposures even before conception can affect gene expression and long-term health outcomes.
  • Yet, formal support systems typically begin only around age three through Anganwadi centres or private preschools, well after the most critical developmental window has passed.
  • The absence of parental support for responsive caregiving, stimulation and emotional bonding during the first 1,000 days represents a significant policy blind spot.
  • To address these gaps, India must transition from fragmented programmes to an integrated ECCD framework that spans preconception to eight years of age.
  • Key components include structured preconception counselling, nationwide parental education, growth and developmental milestone monitoring, quality early learning systems for children aged two to five, and collaboration across health, nutrition and education sectors.
  • Schools, given their institutional reach, can evolve into holistic hubs for learning, nutrition and well-being rather than merely instructional spaces. 

The Way Forward: Towards a Societal and Policy Movement

  • Realising such a transformation requires both state action and societal ownership. ECCD must become a subject of public conversation within homes, communities, workplaces and schools.
  • Non-profit organisations, philanthropic institutions and the private sector can play critical roles in shaping ecosystems of care and learning.
  • At the governmental level, effective coordination among ministries, including Health, Education and Women and Child Development, is essential.
  • A dedicated inter-ministerial mission on ECCD could formalise responsibilities, streamline investments and ensure continuity across election and policy cycles.

Conclusion

  • India’s long-term developmental trajectory will depend less on what it promises its children and more on what it invests in them during their earliest years.
  • ECCD is not an optional add-on to India’s growth strategy; it is its foundation.
  • The health, skills and productivity of future generations will ultimately determine whether India’s ambitions of becoming a developed nation are realised.
  • A citizen-led movement for early childhood development, backed by robust policy and institutional frameworks, may prove to be the missing link in India’s journey towards inclusive and sustainable prosperity.
Editorial Analysis

Current Affairs
Jan. 15, 2026

Key Facts about Konda Reddi Tribe
At least 38 thatched houses belonging to members of the Konda Reddi tribe have been gutted in a fire mishap reportedly due to a short circuit at Sarlanka village in Prathipadu Mandal in Kakinada district, Andhra Pradesh, recently.
current affairs image

About Konda Reddi Tribe:

  • Konda Reddis is a Particularly Vulnerable Tribal Group (PVTG) inhabiting the banks situated on either side of the Godavari River in the hilly and forest tracts of the East and West Godavari and Khammam districts of Andhra Pradesh.
  • Language: Their mother tongue is Telugu in its purest and chaste form and a unique accent.
  • Religion:
    • The primary religion practiced by the Konda Reddi is Folk Hinduism, characterized by local traditions and cults of local deities worshiped at the community level.
    • Their main festivals are Ugadi, Akshade, and Dussehra.
  • Family and Marriage:
    • The family is patriarchal and patrilocal. Monogamy is a rule, but polygamous families are also found.
    • Marriage by negotiations, by love and elopement, by service, by capture, and by exchange are socially accepted ways of acquiring mates.
  • Political Organization:
    • They have their own institution of social control called ‘Kula Panchayat’.
    • Each village has a traditional headman called ‘Pedda Kapu’.
    • The office of the headman is hereditary, and the headman is also the Pujari (priest) of the village deities.
  • Livelihood:
    • They are primarily shifting cultivators and largely depend on the flora and fauna of forest for their livelihood.
    • They eat a variety of tubers, roots, leaves, wild fruits,
    • They collect and sell non-timber forest produce like tamarind, adda leaves, myrobolan, broomsticks etc., to supplement their meagre income.
    • They largely cultivate jowar, which is their staple food.
    • The Konda Reddi tribe’s way of life largely revolves around the cow, which is a source of sustenance for them.
    • These tribal people are aggressive in the cultivation of commercial crops such as cashew, niger, chilli, and cotton under the Podu cultivation method.
  • The tribe has adopted a unique circular-shaped architecture for housing. The houses, built with circular mud walls and thatched roofs, resemble the Bhunga architecture of Gujarat’s Kachchh region.
Geography

Current Affairs
Jan. 15, 2026

What is the Miyawaki Method?
The Miyawaki method can be used in cities where green space has thinned out over decades.
current affairs image

About Miyawaki Method:

  • This method of afforestation was developed by renowned Japanese botanist Akira Miyawaki in the 1970s.
  • It is a revolutionary method for creating dense forests in limited spaces.
  • It is often referred to as the ‘pot plantation method’, it involves planting trees and shrubs close to one another to accelerate their growth.
  • The competition for sunlight encourages trees to grow more vertically and less laterally.
  • It emphasises planting only plant species native to the local area. This fosters a more resilient and naturally balanced ecosystem.
  • Plants grow 10 times faster with this technique, making it a practical solution for urban areas.
  • They are much denser and house much more biodiversity — just like ancient, primordial forests.
  • For the first two to three years, the forest requires regular watering, weeding, and monitoring.
  • After this period, the forest becomes self-sustaining and requires minimal intervention.
  • Advantages:
    • It improves soil quality, enhances biodiversity, and accelerates forest development.
    • Trees planted using the Miyawaki technique absorb more carbon, grow faster, and support richer biodiversity compared to traditional forests.
    • In urban settings, this technique has transformed polluted, barren lands into green ecosystems.
    • It has successfully managed industrial waste, reduced dust and foul odours, and curbed air and water pollution.
    • Additionally, it prevents soil erosion and promotes ecological balance, making it an effective tool for environmental restoration.
Environment

Current Affairs
Jan. 15, 2026

What is Huntington's Disease (HD)?
Huntington's disease (HD) has long been impossible to cure, but new research is finally giving fresh hope.
current affairs image

About Huntington's Disease (HD):

  • It is a rare hereditary disorder in which brain cells, or neurons, in certain areas of your brain start to break down.
    • The destruction of nerve cells happens in the basal ganglia, or the region of your brain that regulates your body’s movements.
    • It also affects the brain cortex (surface of your brain) that regulates your thinking, decision-making, and memory.
  • As the neurons degenerate, the disease can lead to emotional disturbances, loss of intellectual abilities, and uncontrolled movements.
  • What causes HD?
    • A genetic mutation of the HTT gene causes HD. If one of your parents has HD, you have a 50% chance of also developing it.
    • The HTT gene makes a protein called huntingtin. This protein helps your nerve cells (neurons) function.
    • If you have HD, your DNA doesn’t have all the information needed to make the huntingtin protein.
    • As a result, these proteins grow in an abnormal shape and destroy (instead of help) your neurons.
    • Your neurons die because of this genetic mutation.
  • There are two main types of HD:
    • Adult-onset: This is the most common Symptoms usually start after age 30.
    • Early-onset (juvenile Huntington’s disease): This rare type affects children and teenagers. Symptoms appear before age 20.
  • Symptoms:
    • Common symptoms include uncontrollable dance-like movements (chorea) and abnormal body postures, as well as problems with behavior, emotion, thinking, and personality.
    • Other symptoms may include tremor (unintentional back-and-forth movement in the person’s muscles) and unusual eye movements. The eye movements can happen early in the disease.
    • These symptoms get worse over time.
    • As HD progresses, you will need constant assistance and supervision because of the debilitating nature of the disease.
  • Treatment: There is no treatment that can stop or reverse HD, but health care providers can offer medications to help with certain symptoms.
Science & Tech
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