Caenorhabditis elegans

May 13, 2024

Researchers found that once C. elegans worms eat a disease-causing strain of bacteria, its children inherited the 'knowledge' to avoid making the same mistake — up to four generations.

About Caenorhabditis elegans:

  • It is a nematode worm which is a small, relatively simple, and precisely structured organism. It grows within 3-5 days from a fertilised egg to a millimetre-long adult, and it has informed profound insights into the human body, as well as biology. 
  • It is widely used in research to understand neuronal and molecular biology. It was the first multicellular organism to have its full genome sequenced and neural wiring mapped. 
  • It has two sexes—a hermaphrodite and a male.
    • The hermaphrodite can be viewed most simply as a female that produces a limited number of sperm: she can reproduce either by self-fertilization, using her own sperm, or by cross-fertilization after transfer of male sperm by mating.
    • Self-fertilization allows a single heterozygous worm to produce homozygous progeny.

What are Nematodes?

  • These are among the most abundant animals on Earth. They occur as parasites in animals and plants or as free-living forms in soil, fresh water, marine environments, and even such unusual places as vinegar, beer malts, and water-filled cracks deep within Earth’s crust.
  • Features:
    • These are bilaterally symmetrical, elongate, and usually tapered at both ends.
    • Some species possess a pseudocoel, a fluid-filled body cavity between the digestive tract and the body wall.
    • They have been reported from every continent on earth and occur in deserts, swamps, the oceans, the tropics and Antarctica.
    • Nematode parasites of animals occur in almost all organs of the body, but the most common sites are in the alimentary, circulatory and respiratory systems.

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