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Ehlers-Danlos Syndrome

Sept. 26, 2026

Recent researches across the world provided new insights about causes of Ehlers-Danlos Syndrome and its association with hormones level and sleep apnea.

About Ehlers-Danlos Syndrome:

  • It is a group of conditions that affect the connective tissue of the human body, typically loosening or weakening it.
    • Connective tissue supports and provides flexibility to the skin, tendons, ligaments, bones, blood vessels, and organs.
  • EDS is generally inherited and is commonly associated with hypermobility, meaning one’s joints can move past their normal range of motion.
  • Cause: EDS is caused by certain genetic changes and is generally passed down to children by their parents.
  • Types of Ehlers-Danlos Syndrome:
    • Hypermobile EDS (hEDS):
      • It is the most common form of EDS.
      • It shows symptoms such as stretchy, fragile skin, loose and clicky joints that dislocate easily, joint pain, and joint hypermobility.
      • hEDS may also manifest as extreme fatigue, skin that bruises quickly, digestive issues, and poor bladder control etc.
    • Classical EDS:
      • It is less common type of EDS, also exhibits similar symptoms, but it mostly affects the skin.
      • A person with this condition might have very stretchy and fragile skin that bruises easily or splits easily, especially around the elbows, on the forehead, and on the knees.
    • Vascular EDS:
      • It affects one’s internal organs.
      • This results in fragile blood vessels that can tear easily and cause internal bleeding, which can be life-threatening.
      • This condition poses a serious risk of bowel tearing, womb tearing during pregnancy, and lung collapse etc.
    • Kyphoscoliotic EDS (kEDS):
      • It affects the curvature of the spine. It might manifest during early childhood and is also characterised by joint hypermobility and loose joints.
    • Treatment: There is no cure for EDS, but symptoms, especially those of hEDS, can be managed.

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