Haemophilia

About Haemophilia:

• It is a rare, inherited bleeding disorder in which the blood does not clot properly.
• Cause: It is due to low or absent levels of clotting factors, mainly factor VIII in haemophilia A and factor IX in haemophilia B.
• Risk: Haemophilia is typically inherited in an X-linked recessive pattern, meaning it predominantly affects males, while females are usually carriers. 
• Research has shown that nearly one-third of haemophilia cases arise from spontaneous mutations, meaning the condition can occur even without a known family history. 
• Symptoms:
  • Individuals with severe haemophilia often experience frequent spontaneous bleeding episodes.
  • Common manifestations include prolonged bleeding, easy bruising, and frequent nosebleeds,
  • In rare but serious cases, bleeding can occur in critical areas such as the brain.
• Treatment: The standard treatment is clotting factor replacement therapy, administered either to control active bleeding or as a preventive measure.