Heliobacter pylori

Dec. 28, 2024

Researchers have found a way to develop FELUDA as a point-of-care diagnostic service at a minimal cost for detection of H. pylori and its mutations in dyspeptic patients from rural areas of India, with minimal or no access to diagnostic laboratories.

About Heliobacter pylori:

  • It is a common type ofbacteria that grows in the digestive tract of human and tends to attack the stomach lining. 
  • It is adapted to live in the harsh, acidic environment of the stomach.
  • It infects a person usually during childhood. Its infections are usually harmless, but they are responsible for most ulcers in the stomach and small intestine, called peptic ulcers.
  • Infections with  pyloriaffect over 43 percent of the world’s population with a wide range of gastrointestinal disorders, including peptic ulcers, gastritis, dyspepsia and even gastric cancer.
  • How it survives in stomach?
  • This bacterium can change the environment around it and reduce the acidity so it can survive more easily.
  • The spiral shape of pylori allows it to penetrate the stomach lining, where it’s protected by mucus and the body’s immune cells cannot reach it. 
  • When signs or symptoms do occur with pylori infection, they are typically related to gastritis or a peptic ulcer and may include:
  • An ache or burning pain in stomach (abdomen)
  • Nausea, loss of appetite and unintentional weight loss etc.
  • Treatment: It can be treated with a combination of antibiotics and a proton-pump inhibitor. This treatment is sometimes referred to as triple therapy.
    • The proton pump inhibitor includes esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole sodium.
    • Antibiotics includes clarithromycin, metronidazole, amoxicillin.

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