Human African Trypanosomiasis

Aug. 10, 2025

Recently, the World Health Organisation (WHO) certified Kenya as having eliminated Human African trypanosomiasis, also known as sleeping sickness.

About Human African Trypanosomiasis:

  • It is a parasitic diseasetransmitted through the bite of infected tsetse flies.
  • It is also known as sleeping sickness and is endemic in sub-Saharan Africa.
  • Symptoms of Human African Trypanosomiasis
    • It shows initially symptoms such as fever, headaches, and joint pain, but can progress to neurological issues like confusion, disrupted sleep, and behavioural changes.
    • First signs and symptoms emerge a few weeks or months after infection. The disease develops rapidly with multi-organ invasion, including the brain.
  • It takes 2 forms, depending on the subspecies of the infecting parasite:
    • Trypanosoma brucei gambiense:It is found in 24 countries of west and central Africa, currently accounts for 92% of reported cases and causes a chronic illness.
    • A person can be infected for months or even years without major signs or symptoms. When evident symptoms emerge, often the disease is advanced with the central nervous system already affected.
    • Trypanosoma brucei rhodesiense:It is found in 13 countries of eastern and southern Africa accounts for 8% of reported cases and causes an acute disease.
  • Who is at risk? It is more prevalent amongst rural populations which depend on agriculture, fishing, animal husbandry or hunting are the most exposed.
  • Till today, WHO has validated the elimination of the gambiense form of HAT in seven countries: Togo (2020), Benin (2021), Ivory Coast (2021), Uganda (2022), Equatorial Guinea (2022), Ghana (2023) ,Chad (2024) and Guinea (2025).

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