INFLAMMAGEING

July 22, 2020

As the most severe Covid-19 cases have occurred mostly in older people, researchers are investigating whether inflamm-ageing has a role in it?

About:

  • Inflamm-ageing is a chronic low-grade inflammation that develops with advanced age.

  • While inflammation is essential to the immune response, inflammageing is not. It is believed to accelerate the process of biological aging and to worsen many age-related diseases.

  • The major cause of inflamm-ageing is accumulation of misplaced and misfolded self-molecules from damaged cells. These molecules are recognized by receptors of innate immune cells which leads to their activation and consequently to inflammation.