A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against aggressive brain cancer.
About Vitamin B3:
Vitamin B3, or Niacin, is a water-soluble vitamin.
Water-soluble vitamins dissolve in water. Leftover amounts of the vitamin leave the body through the urine.
The body keeps a small reserve of these vitamins, but they have to be taken on a regular basis to maintain the reserve.
It is naturally present in many foods, added to some food products, and available as a dietary supplement.
The body gets niacin through food, but it also makes small amounts from the amino acid tryptophan, which can be found in protein sources like turkey and other animal foods.
The two most common forms of niacin in food and supplements are nicotinic acid and nicotinamide.
Functions:
Niacin works in the body as a coenzyme, with other enzymes dependent on it for various reactions.
Niacin helps to convert nutrients into energy, create cholesterol and fats, create and repair DNA, and exert antioxidant effects.
Due to Niacin's positive effects on cholesterol levels, it may help prevent heart disease.
Additionally, it may reduce oxidative stress and inflammation, which are associated with atherosclerosis, or the hardening of the arteries.
Food Sources: It is found in many foods, both from animals and plants.
Red meat: beef, beef liver, pork
Poultry
Fish
Brown rice
Fortified cereals and breads
Nuts, seeds
Legumes
Bananas
Deficiency:
A severe niacin deficiency leads to pellagra, a condition that causes a dark, sometimes scaly rash to develop on skin areas exposed to sunlight; bright redness of the tongue; and constipation/diarrhea.
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