Kyasanur Forest Disease

April 14, 2025

Kyasanur Forest Disease (KFD), or "monkey fever," is currently surging in Karnataka's Shivamogga and Chikkamagaluru districts recently.

About Kyasanur Forest Disease (KFD):

  • KFD, also referred to as Monkey Fever, is a tick-borne viral haemorrhagic disease, which can be fatal to humans and other primates.
  • It is mostly found in southern India. The disease was first reported from the Kyasanur Forest of Karnataka in 1957, hence, it is known as KFD.
  • The causal agent, Kyasanur Forest Disease Virus (family Flaviviridae, genus Flavivirus), is a member of the tick-borne encephalitis (TBE) complex.
  • The epidemic period usually begins in October or November and peaks from January to April, then declines by May and June.
  • Transmission:
    • Hard ticks (Hemaphysalis spinigera) spread the KFD virus to people and to animals, like monkeys and rodents.
    • No person-to-person transmission has been established yet.
  • Symptoms:
    • Most people with KFD have a sudden onset of chills, fever, and headache.
    • Severe muscle pain, vomiting, gastrointestinal symptoms, and bleeding can follow 3 or 4 days after symptoms begin.
    • Most patients recover one to two weeks after symptoms begin.
    • About 10 to 20% of patients experience a second wave of symptoms, including severe headache, mental disturbances, tremors, and vision problems.
    • Between 5 and 10% of people who are known to be affected by KFD die.
  • Treatment:
    • There is no cure for KFD.
    • Supportive care is crucial, including fluid balance, providing oxygen, managing blood pressure, and treating additional infections.
  • Vaccine: A vaccine for KFD is available and recommended in the parts of India where KFD is found.
    • The existing vaccine is a formalin-inactivated whole virus vaccine, but it requires booster doses and has shown limited efficacy in some cases.

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