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Naegleria fowleri

Sept. 20, 2026

Scientists have figured out how Naegleria fowleri amoebae go from the nose to the brain, with N. gruberi as a proxy.

About Naegleria fowleri:

  • It is commonly known as “brain-eating amoeba,” is a single-cell organism.
  • Habitat: It thrives in warm freshwater lakes, ponds and rivers. It can also survive in poorly maintained swimming pools in rare cases.
  • Only one species of Naegleria, Naegleria fowleri, infects people.
  • It causes Primary amoebic meningoencephalitis or PAM.
  • Humans Infection Process:
    • It is typically acquired through the nasal passage and mouth.
    • The amoeba then migrates through the olfactory nerve to the brain, where it causes severe inflammation and destruction of brain tissue.
    • The Naegleria fowleri infection does not spread from person to person, nor does it manifest symptoms when contracted in other forms.
  • The infection is primarily associated with a warm freshwater environment, especially during hot summer months when water temperatures are higher.

Key facts about Primary Amoebic Meningoencephalitis

  • It is caused by Naegleria fowleri. 
  • It is non-communicable and people cannot get infected with Naegleria fowleri from drinking water contaminated with the amoeba.
  • Treatment:
    • There are no effective treatments for the disease yet.
    • At present, doctors treat it with a combination of drugs, including amphotericin B, azithromycin, fluconazole, rifampin, miltefosine, and dexamethasone.

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