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Nafithromycin

Oct. 19, 2025

Recently, the Union Science and Technology Minister informed that India has developed its first indigenously discovered antibiotic, Nafithromycin.

About Nafithromycin:

  • It is an antibiotic which has been developed with the support of “Biotechnology Industry Research Assistance Council” (BIRAC).
  • It has been brought to market under the trade name “Miqnaf”.
  • It is the first molecule entirely conceptualized, developed and clinically validated in India.
  • It is the country’s first indigenously developed antibiotic aimed at tackling Antimicrobial Resistance (AMR).
  • It is effective against resistant respiratory infections, particularly useful for cancer patients and poorly controlled diabetics.
  • This innovation is designed to treat Community-Acquired Bacterial Pneumonia (CABP).
  • Nafithromycin’s efficacy stands out as it targets both typical and atypical pathogens, offering a potent solution where no new antibiotic in this class has been developed worldwide for over three decades.

What is Antimicrobial Resistance (AMR)?

  • It occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial medicines.
  • As a result of drug resistance, antibiotics and other antimicrobial medicines become ineffective and infections become difficult or impossible to treat.
  • It increases the risk of disease spread, severe illness, disability and death.
  • AMR is a natural process driven by genetic changes in pathogens over time, its spread is significantly accelerated by human activities.

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