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Nitric Oxide

Feb. 17, 2026

In a study published in Science Translational Medicine, researchers found that a high dose of inhaled nitric oxide reduced drug-resistant Pseudomonas in a large-animal ICU model.

About Nitric Oxide:

  • It exists in a gaseous state and is composed of one nitrogen and one oxygen atom.
  • Formation: It is formed through nitrogen oxidation.
  • It can be created when lightning occurs, uniting nitrogen and oxygen in the air, or commercially by burning ammonia.
  • Properties of Nitric Oxide:
    • It is a colorless, toxic gas.
    • It is noncombustible but accelerates the burning of combustible material.
    • It can be found in the natural environment and within parts of the human body.
  • Roles of Nitric Oxide:
    • It plays important chemical signaling roles in humans and animals, plus some medical uses.
    • In animals, nitric oxide transmits signals to cells in the cardiovascular, nervous, and immune systems.
    • The body synthesizes it from the amino acid L-arginine with the help of nitric oxide synthase.
    • It helps regulate blood pressure by dilating blood vessels and acts as a neurotransmitter. 
    • Impact on Environment: Nitric oxide is generated by automotive engines and thermal power plants, making it a serious air pollutant.

 

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