PAXLOVID

Nov. 8, 2021

Pfizer announced trial results for its investigational Covid-19 oral antiviral candidate, Paxlovid, saying it significantly reduced hospitalisation and death.

About:

  • It is an investigational SARS-CoV-2 “protease inhibitor antiviral therapy”.

  • It inhibits viral replication at proteolysis, a stage that occurs before viral replication.

  • It is “designed to be administered orally so that it can be prescribed at the first sign of infection or at first awareness of an exposure, potentially helping patients avoid severe illness.”

  • Pfizer said it has entered into advance purchase agreements with “multiple countries and is in negotiations with several others”.