About Smart Insulin (NNC2215):
- The newly developed insulin named NNC2215 comprises two parts: a ring-shaped structure, and a molecule with a similar shape to glucose called a glucoside.
- How does it work?
- When blood sugar levels are low, the glucoside binds to the ring, keeping the insulin in an inactive state to prevent further lowering of blood sugar.
- But, as blood glucose rises, the glucoside is replaced by glucose itself, triggering the insulin to shift its shape and become active, helping bring blood sugar levels down to safer ranges.
- Researchers who developed NNC2215 found it to be as effective as human insulin at lowering blood glucose in rats and pigs.
Diabetes
- Diabetes is a chronic disease that occurs when the pancreas can no longer make insulin, or the body cannot make good use of the insulin it produces.
- Insulin is a hormone that regulates blood glucose.
- Types of Diabetes
- Type 1 diabetes: It often starts in childhood, occurs when the pancreas do not produce insulin (or enough insulin).
- Type 2 diabetes: It results from the body’s ineffective use of insulin that it produces.
- Gestational diabetes (GDM): It is a type of diabetes that consists of high blood glucose during pregnancy and is associated with complications for both mother and child.
