SPIKE PROTEIN

July 27, 2020

Researchers have found that the spike protein of SARS-CoV-2 changes its form after it attaches itself to a human cell, folding in on itself and assuming a rigid hairpin shape. The researchers believe the knowledge can help in vaccine development.

About:

  • It is a protein that protrudes from the surface of a coronavirus, like the spikes of a crown or corona — hence the name ‘coronavirus’.

  • In the SARS-CoV-2 coronavirus, it is the spike protein that initiates the process of infection in a human cell.

  • It attaches itself to a human enzyme, called the ACE2 receptor, before going on to enter the cell and make multiple copies of itself.