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What is Amyotrophic Lateral Sclerosis (ALS)?

Aug. 7, 2026

People exposed to pesticides at work may be significantly more likely to develop Amyotrophic Lateral Sclerosis (ALS), according to a new review of global evidence published.

About Amyotrophic Lateral Sclerosis (ALS):

  • It is a progressive neurological disorder that damages the nerve cells controlling voluntary muscle movement. These nerve cells are called motor neurons.
    • One group, called upper motor neurons, extends from the brain to the spinal cord.
    • The second group, called lower motor neurons, extends from the spinal cord to muscles throughout the body.
    • ALS causes both groups of motor neurons to gradually deteriorate and then die.
    • When motor neurons are damaged, they stop sending messages to the muscles. As a result, the muscles can't function.
  • ALS is often called Lou Gehrig's disease after the baseball player who was diagnosed with it.
    • Cause:
      • The exact cause is still not known in most people.
      • In a small percentage of people, ALS is inherited from a parent.
    • Treatment:
      • Currently, there’s no treatment to reverse damage to motor neurons or cure ALS.
      • But some treatments may slow progression of the disorder, improve quality of life, and extend survival.

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