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What is C-reactive protein (CRP)?

Jan. 6, 2026

Accumulating evidence over the past two decades demonstrates that a biomarker called C-reactive protein – which signals the presence of low-grade inflammation – is a better predictor of risk for heart disease than cholesterol.

About C-reactive protein (CRP):

  • It is a protein made by the liver.
  • The level of CRP increases when there's inflammation in the body.
  • A CRP test measures the level of CRP in blood.
  • By measuring the levels of CRP in blood, a CRP test can tell the health care provider about the inflammation of the body.
  • High CRP levels may mean an acute or chronic health condition, such as:
    • Infections from bacteria or viruses.
    • Inflammatory bowel disease, disorders of the intestines that include Crohn's disease and ulcerative colitis.
    • Autoimmune disorders, such as lupus, rheumatoid arthritis, and vasculitis.
    • Lung diseases, such as asthma.
  • Smoking and exposure to environmental toxins such as polluted air and hazardous waste can also cause high CRP levels.

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