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What is Diphtheria?

April 25, 2026

After decades of being largely under control, diphtheria — a serious but vaccine-preventable disease — is making an unexpected return in parts of Australia.

About Diphtheria:

  • It is a highly contagious bacterial infection that can attack the upper respiratory tract and less often the skin.
  • It is caused by strains of bacteria called Corynebacterium diphtheriae that make a toxin.
  • The bacterium usually multiplies on or near the surface of the throat or skin.
  • There are two main types of diphtheria:
    • Classical respiratory diphtheria: It may affect your nose, throat, tonsils, or larynx (voice box). It’s the most common type.
    • Skin (cutaneous) diphtheria: It causes a skin rash, sores, or blisters. They can appear anywhere on your body. Cutaneous diphtheria is more common in tropical climates. Overall, it’s rare.
  • Transmission:
    • It can spread from person to person, usually through respiratory droplets, like from coughing or sneezing.
    • People can also get sick from touching infected open sores or ulcers in case of cutaneous diphtheria.
    • Some people may not develop disease manifestations but can still transmit the bacteria to others.
  • Treatment:
    • Neutralization of unbound toxin with Diphtheria Antitoxin (DAT).
    • Antibiotics to prevent further bacterial growth;
    • Monitoring and supportive care to prevent and treat complications, e.g. airway obstruction, myocarditis.
    • It is a vaccine-preventable disease, but multiple doses and booster doses are needed to produce and sustain immunity.

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