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What is Dopamine?

April 28, 2026

Researchers recently showed for the first time that dopamine dysfunction in the entorhinal cortex, a critical memory-related brain region, contributes directly to impaired memory formation.

About Dopamine:

  • Dopamine is a hormone and a type of neurotransmitter, or chemical messenger, made in your brain.
  • Your nervous system uses it to send messages between nerve cells. These messages also travel between your brain and the rest of your body
  • This unique neurotransmitter affects your body, brain, and behavior.
  • Dopamine is the chemical that mediates pleasure in the brain.
    • It is released when your brain is expecting a reward.
    • When you come to associate a certain activity with pleasure, mere anticipation may be enough to raise dopamine levels.
  • It's a big part of our unique human ability to think and plan. It helps us focus, work towards goals, and find things interesting.
  • Dopamine also plays a role in these functions:
    • learning and attention
    • mood
    • movement
    • heart rate
    • kidney function
    • blood vessel function
    • sleep
    • pain processing
    • lactation
  • High or low dopamine levels are associated with diseases including Parkinson’s disease, restless legs syndrome, and attention deficit hyperactivity disorder (ADHD).
  • Dopamine is also made in other parts of your body, where it acts as a hormone.
  • Dopamine acts as a hormone to help:
    • relax or tighten your blood vessels when needed
    • control your salt levels and urine production
    • control how much insulin you make
    • slow down some parts of your digestion
  • Dopamine is found in humans as well as animals, including both vertebrates and invertebrates.

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