What is Glioblastoma?

Aug. 5, 2024

In an innovative new study of glioblastoma, scientists used Artificial Intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them.

About Glioblastoma:

  • It is a type of cancer that starts as a growth of cells in the brain or spinal cord.
  • Like all cancers, glioblastoma is caused by DNA mutations that result in uncontrolled cell growth. The underlying causes for these genetic cell mutations are largely unknown. 
  • Glioblastoma forms from cells called astrocytes that support nerve cells.
    • Astrocytes help give your brain the nutrients it needs. 
  • Glioblastoma tumors make their own blood supply, which helps them grow. It's easy for them to invade normal brain tissue.
  • It grows quickly and can invade and destroy healthy tissue.
  • It can happen at any age. However, it tends to happen more often in older adults.
  • It accounts for almost half of all cancerous brain tumors in adults.
  • Symptoms:
    • Glioblastoma symptoms may include headaches that keep getting worse, nausea and vomiting, blurred or double vision, trouble speaking, altered sense of touch, and seizures.
    • There also may be trouble with balance, coordination, and moving parts of the face or body.
  • Treatment:
    • There's no cure for glioblastoma. Treatments might slow cancer growth and reduce symptoms.
    • The main treatments for glioblastomas are surgery, radiotherapy and chemotherapy