What is Guillain-Barre syndrome?

July 11, 2023

Recently, Peru has declared a state of national emergency amid a surge in patient suffering from Guillain-Barré syndrome.

About Guillain-Barre syndrome:

  • It is a rare autoimmune disorder where the body's immune system mistakenly attacks the peripheral nerves.
  • It is more common in adults and males, but it can affect people of all ages.
  • Symptoms
    • The first symptoms of Guillain-Barré syndrome include weakness or tingling sensations. They usually start in the legs, and can spread to the arms and face.
    • For some people, these symptoms can lead to paralysis of the legs, arms, or muscles in the face.
  • Causes
    • It is often preceded by an infection.
    • This could be a bacterial or viral infection.
    • The most frequently associated infections include Campylobacter jejuni, Epstein-Barr virus (EBV), cytomegalovirus (CMV), and the bacteria responsible for pneumonia and urinary tract infections.
    • It may also be triggered by vaccine administration or surgery.
  • Diagnosis
    • There is no known cure for this syndrome.
    • The most commonly used treatment is intravenous immunoglobulin (IVIG), which is made from donated blood that contains healthy antibodies.
    • This helps calm down the immune system's attack on the nerves.