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What is Hyperkeratosis?

July 13, 2026

Experts say feeding sweets to monkeys at Jaipur's Galtaji temple is causing hyperkeratosis among them.

About Hyperkeratosis:

  • Hyperkeratosis is a condition that causes skin to thicken in certain places.
  • The thickening occurs when body produces too much keratin, a protein found in your skin’s outer layer.
    • Keratin helps to protect the body against infiltration by water and other chemical and biological agents with which it comes in contact every day.
  • Hyperkeratosis can affect any area of body. Anyone can get hyperkeratosis. Some people have it at birth. Other people develop this condition as children or adults.
  • There are two main types of hyperkeratosis:
    • Non-pressure-related hyperkeratosis: Thickening of your skin due to genetics.
    • Pressure-related hyperkeratosis: Thickening of your skin due to inflammation, irritation, or pressure.
  • Several factors may cause hyperkeratosis, including:
    • Allergies.
    • Autoimmune diseases.
    • Chronic inflammation of the skin (dermatitis).
    • Infections of the skin, including HPV (human papillomavirus).
    • Genetics.
    • Medications, including chemotherapy.
    • Pressure or rubbing of your skin.
    • Psoriatic arthritis.
    • Reactions to chemicals, including tattoo ink.
    • Skin infections.
    • Sun exposure.
    • Vitamin A deficiency.
  • Forms of hyperkeratosis include:
    • actinic keratosis, which causes rough, sandpaper-like patches of skin to develop as a result of excess skin exposure
    • calluses
    • corns
    • eczema
    • epidermolytic hyperkeratosis, an inherited skin disorder present at birth
    • lichen planus, a condition that causes white patches to grow on the inside of the mouth
    • plantar warts
    • psoriasis
    • Warts

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