What is Mpox?

Feb. 13, 2025

The scientific community is divided on whether mpox should be given the label of a sexually transmitted disease (STD), with targeted public health interventions to contain it.

About Mpox:

  • Mpox, previously known as monkeypox, is a zoonotic viral illness caused by the monkeypox virus, a species of the genus Orthopoxvirus.
  • Mpox is characterized by rash or skin lesions that are usually concentrated on the face, palms of the hands, and soles of the feet.
  • The first human case of mpox was recorded in 1970 in the Democratic Republic of the Congo (DRC).
  • There are two known subtypes of mpox:
    • Clade I: It is endemic to Central Africa. It tends to cause more serious illness than clade II. Recent outbreaks of clade I have been less deadly.
    • Clade II: It is endemic to East Africa. There’s been a global outbreak of clade II mpox since 2022. It’s less likely to be fatal than clade I.
  • Transmission:
    • MPXV is transmitted to people by close contact with infected animals or people or by touching virus-contaminated materials.
    • It enters the body through (often invisible) injuries or wounds in the skin, or the mucous membranes.
    • Mpox can be passed from one person to another during sexual contact.
    • During pregnancy, the virus may be passed to the fetus, or to the newborn during or after birth.
  • Symptoms:
    • Common symptoms of mpox are a skin rash or mucosal lesions, which can last 2–4 weeks, accompanied by fever, headache, muscle aches, back pain, low energy and swollen lymph nodes.
    • Mpox symptoms often resolve on their own without the need for treatment.
  • Treatment:
    • There are no specific treatments for monkeypox virus infection.
    • Treatment for most people with mpox is to relieve symptoms.

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