What is Sickle cell anemia?

Feb. 2, 2023

Union Finance Minister recently announced the Central Government’s plan to launch a mission to eliminate sickle cell anemia by 2047.

About Sickle cell anemia:

  • It is an inherited blood disorder.
  • It affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. 
  • People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
  • These sickle cells also become rigid and sticky, which can slow or block blood flow.
  • What causes it?
    • The cause of Sickle cell disease is a defective gene, called a sickle cell gene.
    • A person will be born with sickle cell disease only if two genes are inherited—one from the mother and one from the father.
  • Symptoms:
    • Early stage: Extreme tiredness or fussiness from anemia, painfully swollen hands and feet, and jaundice.
    • Later stage: Severe pain, anemia, organ damage, and infections.
  • Treatments:
    • The only cure for this disease is bone marrow or stem cell transplantation.
    • However, there are treatments that can help relieve symptoms, lessen complications, and prolong life.