Researchers from Japan recently discovered a self-reinforcing loop between different immune cells that sustains autoimmune responses in patients with Sjögren's disease.
About Sjogren’s Disease:
Sjogren's disease (also called Sjögren’s syndrome) is a chronic autoimmune disorder where the immune system mistakenly attacks its own moisture-producing glands.
It typically attacks the glands that produce tears, saliva, and sweat.Other parts of the body may also be affected.
Cause:
The exact cause of Sjogren's syndrome is unknown, though there seems to be a genetic influence.
It is thought that factors such as viral infections, stress, and hormone changescan trigger symptoms of Sjogren's syndrome.
Sjogren syndrome can happen at any age. But most people are older than 40 at the time of diagnosis.
Ninety percent (90%) of adults diagnosed with Sjogren’s are women.
Sjogren’s can occur alone or in association with other autoimmune diseases, most commonly lupus and rheumatoid arthritis (RA).
Symptoms: People with Sjogren's syndrome can have:
dry eyes, which may also feel painful, burning, itchy, or gritty
a dry mouth, making it difficult to swallow, speak, or eat dry foods
swelling of the glands in the face and neck areas
Some people with Sjögren's syndrome also notice:
joint pain, swelling and stiffness
dry skin or skin rash
vaginal dryness
persistent dry cough
ongoing fatigue
Sometimes the liver and kidneys are affected. A few people will also develop lymphoma (cancer of the lymph nodes).
Treatment:
There is no cure for Sjögren's syndrome.
Treatment for Sjogren’s disease attempts to relieve the effects of chronic dryness of the mouth and eyes by increasing the lubrication and moisturization of the affected tissues.
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